Recombinant Human Erythropoietin Treatment for Chemotherapy-related Anemia in Children

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Recombinant human erythropoietin treatment for chemotherapy-related anemia in children.

OBJECTIVE The efficacy and safety of recombinant human erythropoietin (rHuEPO) treatment in chemotherapy-induced anemia in children were investigated. rHuEPO is used to treat chemotherapy-induced anemia. Several studies recommend 150 to 300 IU/kg rHuEPO for 2 to 8 months. There are only a few controlled trials in children and no precise data about the optimal dose and duration of rHuEPO treatme...

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Recombinant Human Erythropoietin in Children with Solid Tumors and Chemotherapy-induced Anemia

Background: In patients undergoing chemotherapy for cancer, anemia is part of the progression of the disease. Considering the effects of anemia on quality of life of the patients, the prevention and treatment of chemotherapy-induced anemia is crucial. This study was aimed to evaluate the efficacy of recombinant human erythropoietin in reducing the need for blood transfusion in children with sol...

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The Efficacy of Recombinant Human Erythropoietin in Treatment Chemotherapy Induced Anemia in Children Diagnosed with a Solid Cancer

Background Recombinant human erythropoietin (rHuEPO) treatment can increase hemoglobin levels and decrease transfusion requirements. This study aims to investigate how blood transfusion influences Hemoglobin levels in patients receiving rHuEPO for 12 weeks. Materials and Methods This was a case-control study of 60 patients less than 15 years with anemia and a solid tumor in any location betw...

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Recombinant Human Erythropoietin in Cancer-Related Anemia

The clinical development of recombinant human erythropoietin (rHuEPO) has had a remarkable impact on the clinical practice of oncology. A decade ago, randomized, placebo-controlled trials in anemic cancer patients demonstrated that rHuEPO resulted in an improvement in hemoglobin and hematocrit, a reduction in transfusion requirements, and improvement in quality-of-life (QOL) end points. Based o...

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the efficacy of recombinant human erythropoietin in treatment chemotherapy induced anemia in children diagnosed with a solid cancer

background recombinant human erythropoietin (rhuepo) treatment can increase hemoglobin levels and decrease transfusion requirements. this study aims to investigate how blood transfusion influences hemoglobin levels in patients receiving rhuepo for 12 weeks. materials and methods this was a case-control study of 60 patients less than 15 years with anemia and a solid tumor in any location between...

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ژورنال

عنوان ژورنال: PEDIATRICS

سال: 1999

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.103.2.e16